Because of these side effects, doses given to women and children are minimized and people are usually monitored for virilization and growth abnormalities. Oxandrolone may disrupt growth in children, reducing their adult height. Women who are administered oxandrolone may experience virilization, irreversible development of masculine features such as voice deepening, hirsutism, menstruation abnormalities, male-pattern hair loss, and clitoral enlargement. See also: Anabolic steroid § Adverse effects When taken by pregnant women, oxandrolone may have unintended effects such as masculinization on the fetus. Like other AASs, oxandrolone may worsen hypercalcemia by increasing osteolytic bone resorption. Many also value oxandrolone's low hepatotoxicity relative to most other orally active AASs. It is much more anabolic than androgenic, so women and those seeking less intense steroid regimens use it particularly often. Many bodybuilders and athletes use oxandrolone illicitly for its muscle-building effects. Children with idiopathic short stature or Turner syndrome are given doses of oxandrolone far smaller than those given to people with burns to minimize the likelihood of virilization and premature maturation.
Oxandrolone has, therefore, largely been replaced by growth hormone for this use. Although oxandrolone has long been used to accelerate growth in children with idiopathic short stature, it is unlikely to increase adult height, and in some cases may even decrease it. Medical research has established the effectiveness of oxandrolone in aiding the development of girls with Turner syndrome. It is also used in the treatment of idiopathic short stature, anemia, hereditary angioedema, alcoholic hepatitis, and hypogonadism. Oxandrolone improves both short-term and long-term outcomes in people recovering from severe burns and is well-established as a safe treatment for this indication. As of 2016, it is often prescribed off-label to quicken recovery from severe burns, aid the development of girls with Turner syndrome, and counteract HIV/AIDS-induced wasting. It is FDA-approved for treating bone pain associated with osteoporosis, aiding weight gain following surgery or physical trauma, during chronic infection, or in the context of unexplained weight loss, and counteracting the catabolic effect of long-term corticosteroid therapy.
Oxandrolone has been researched and prescribed as a treatment for a wide variety of conditions.
The drug is a controlled substance in many countries, so nonmedical use is generally illicit. In addition to its medical use, oxandrolone is used to improve physique and performance. Oxandrolone was first described in 1962 and was introduced for medical use in 1964. It has strong anabolic effects and weak androgenic effects, which give it a mild side effect profile and make it especially suitable for use in women. The drug is a synthetic androgen and anabolic steroid, hence is an agonist of the androgen receptor (AR), the biological target of androgens such as testosterone and dihydrotestosterone. Side effects of oxandrolone include symptoms of masculinization such as acne, increased hair growth, voice changes, and increased sexual desire.
Oxandrolone, sold under the brand names Oxandrin and Anavar, among others, is an androgen and anabolic steroid (AAS) medication which is used to help promote weight gain in various situations, to help offset protein catabolism caused by long-term corticosteroid therapy, to support recovery from severe burns, to treat bone pain associated with osteoporosis, to aid in the development of girls with Turner syndrome, and for other indications.
0 kommentar(er)
